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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10051 | 5-HT3 antagonist 1 | Others | |
5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor. | |||
T9846 | 5-HT3 antagonist 5 | ||
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound which is a 5-HT 3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT 3 agonist and 2-methyl-5-HT, and exhibits anti-depressant effect in mice [1]. | |||
T8445 | PU02 | PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine | Apoptosis , 5-HT Receptor |
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. | |||
T15414 | GR 113808 | GR-113808 | 5-HT Receptor |
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release. | |||
T67956 | Litoxetine | 5-HT Receptor | |
Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently r... | |||
T4978 | Sarpogrelate hydrochloride | MCI-9042 | 5-HT Receptor |
Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ... | |||
T70623 | Esmirtazapine HCl | ||
Esmirtazapine HCl is the salt form of Esmirtazapine, a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscar... | |||
T64234 | Alosetron (Hydrochloride(1:X)) | ||
Alosetron (GR 68755) Hydrochloride (1:X) is a potent and highly selective 5-HT3 receptor antagonist with anti-inflammatory effects. Alosetron Hydrochloride (1:X) can be used in the study of irritable bowel syndrome (IBS)... | |||
T60437 | PNU-282987 free base | ||
PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM, which is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base... |